This study discusses an estimation framework of spatial interactions at the local (urban) scale - the so-called spatial weights matrix (W). It develops an application to the Portuguese’s Aveiro and Ílhavo municipalities. The work was based on a housing dataset retrieved from the Portuguese real estate portal CASA SAPO (https://casa.sapo.pt/). The dataset was provided by the research project from the University of Aveiro “Fatores Determinantes da Procura de Habitação”, which, after preprocessing, includes a set of basic intrinsic housing attributes (area, time on market, and preservation), the published (asking) price and locational information (real estate market experts’ zones/neighborhoods). The dataset comprises 7288 houses covering the time period from 2005 to 2010.