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Preprint of Prefrontal-Hippocampal Comparator.docx (388.82 kB)
The Prefrontal-Hippocampal Comparator: Volition and Episodic Memory
This review article supports the following: (1) Hippocampal area CA1 serves as an associative match-mismatch comparator, (2) Voluntary movement strengthens episodic memories for goal-directed behavior, (3) Hippocampal theta power serves as a prediction error signal during hippocampal dependent tasks, (4) The self-referential component of episodic memory in humans is mediated by the corollary discharge (efference copy of the action plan developed by prefrontal cortex), and (5) Impairments in the production or transmission of this corollary discharge may contribute to some of the symptoms of schizophrenia.
History
Declaration of conflicts of interest
NoneCorresponding author email
rnuman@scu.eduLead author country
- United States
Lead author job role
- Career College Faculty
Lead author institution
Santa Clara UniversityHuman Participants
- No
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